you can make some educated guesses (e.g. figure out more or less how much videomemory is necesary by adding up the sizes of all your images, rounded up to the nearest power-of-two, times 4 (32 bit + alpha)
e.g. an image that's 512x512 pixels takes up 512x512x4 bytes of video RAM. An image that's 400x200 pixels takes up 512x256x4 bytes of video RAM.
But in the end, the only real way to figure out the minimum specifications is to run on on different computers, and see what the slowest / low end machine is that things still run 'acceptable', and call that your minimum requirement.
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